HealthDay (6/26, Reinberg) reported, "Fat from red meat and dairy products can increase your risk for pancreatic cancer," according to a new study published online in the Journal of the National Cancer Institute (NCI). At present, "pancreatic cancer, which is usually fatal, is the fourth-leading cause of cancer deaths in the United States." The scientific community has been diligent in their identification of various risk factors, "including smoking, diabetes, and obesity," and "some studies have also linked dietary fat to increased risk, but" the NCI team pointed out that "data had been inconclusive."
Aiming to further validate the association, investigators "analyzed a cohort of more than 500,000 people from the National Institutes of Health-AARP Diet and Health Study," according to MedPage Today (6/28, Emery). Study participants "completed a food frequency questionnaire in 1995 and 1996 and were then followed prospectively to track a variety of health outcomes, including pancreatic cancer." During the next six-and-a-half years, "865 men and 472 women were diagnosed with exocrine pancreatic cancer." Yet, among those "who consumed the highest amounts of total fats, the rate of cancer was 53 percent higher for men and 23 percent higher for women, compared to participants with the lowest fat diets." When the data was pooled, the researchers discovered "that total fat consumption was associated with 23 percent higher rates of pancreatic cancer, while high intake of monosaturated fats was associated with 22 percent higher cancer rates."
WebMD (6/26, Hitti) pointed out, however, that it is important to note that the work "doesn't prove that dietary fat was responsible for that, or that meat or dairy products were particularly to blame," because "observational studies like this one show associations, but they don't prove cause and effect." Still, the authors maintained that their "study is in line with the USDA [US Department of Agriculture] guidelines to be prudent and limit fat intake to between 20 and 35 percent of total calories." Nevertheless, lead investigator Rachael Stolzenberg-Solomon, PhD, RD, conceded that "other studies are needed to confirm the findings," a sentiment mirrored by the authors of an accompanying editorial.
The editorialists applaud the NCI team, writing that their "study is well performed, provides high-quality data, and is 'a welcome addition to our understanding of a disease that is in great need of new insights,'" Medscape (6/26, Chustecka) reported. "However, the available epidemiologic and laboratory evidence is insufficient to confirm the importance of animal fats, per se, or even that meat is the important factor, as opposed to other dietary or lifestyle preferences associated with meat consumption."
BBC News (6/26) also covered the study, as did the UK's Guardian (6/28, McKie) and Telegraph (6/26, Devlin).